الانتقال الى المحتوى الأساسي

جامعة الملك عبدالعزيز

KING ABDULAZIZ UNIVERSITY

كلية الطب

تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
“Ultra-structural changes induced in rat kidney by chronic administration of lead acetate”
“Ultra-structural changes induced in rat kidney by chronic administration of lead acetate”
 
لغة الوثيقة : الانجليزية 
المستخلص : Lead is a widespread environmental contaminant, found in air, canned food, drinking water and paints, creating environmental pollution. Lead is capable of damaging vital organs especially the kidneys because it is the main route of lead excretion. The purpose of the present work was to determine the ultra-structural effects of lead acetate on the kidneys of albino rats, who are given lead acetate in their drinking water through oro-gastric intubation in both therapeutic (group A) and sub-lethal (group B) doses for 6 months. The glomerular capillary wall in the kidneys of group A rats showed mild changes in the form of partial fusion of the secondary foot processes of podocytes, while the kidneys of group B rats showed marked changes in the form of diminution of fenestrated endothelia and marked reduction of secondary foot processes of podocytes. The proximal convoluted tubules in the kidneys of group A rats showed mild changes in the form of absence of both basal striations and brush border with disorientation of deep basal infoldings of the cell membrane. The proximal tubules in the kidneys of group B rats showed marked changes in the form of multiple intracytoplasmic vacuoles, multiple lysosomes, multiple degenerated mitochondria and irregular thickened basement membrane. Kidneys of animals left to recover in group A showed complete recovery, while only partial recovery was detected in group B. 
ردمد : 19198720 
اسم الدورية : Al-Azhar Medical Journal 
المجلد : 7 
العدد : 8 
سنة النشر : 2009 هـ
2009 م
 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Sunday, March 28, 2010 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
شريف حسنHassan, Sherif باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 26228.1 1 

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